Generation is non-invasive prenatal testing (NIPT) that screens for chromosomal changes that can affect your baby's future health.

NIPT uses a blood sample from the mother to determine the chance of a chromosomal condition in the developing baby from as early as the 10th week of pregnancy. Generation is highly accurate and safe.

We offer three Generation NIPT options:
Generation, Generation 46 and Generation Plus. 

All options provide information on the chance that your baby is affected by common chromosomal conditions including Down syndrome.

Your doctor can advise on the best Generation test for your personal circumstances.

Genomic Diagnostics provides free genetic counselling for all women/couples who receive a high risk NIPT result.

Generation - $425

Generation 46 - $449

Generation Plus - $799

Generation NIPT Advantages

Collected from 10 weeks throughout pregnancy

The lowest reported test failure rate of any NIPT

NIPT is the most accurate prenatal screening test available for Down, Edwards and Patau syndrome (Trisomy 21, 18 & 13)

Doctors will receive results within 3 - 7 business days of sample arriving at the Genomic Diagnostics' laboratory for Generation and Generation 46.

All screens are analysed in an accredited laboratory*

Only a single tube of blood is drawn

* Generation and Generation 46 are performed in our accredited Australian laboratory. If a Generation Plus test is requested, your sample will be sent to an accredited laboratory in California and results are available in 11 – 15 business days of the sample arriving at the overseas laboratory.

How does Generation NIPT work?

Our genetic information is found in our DNA, on string like structures called chromosomes. Healthy people usually have 46 chromosomes, made up of 23 chromosome pairs (numbered 1 through 22, and either XX or XY).

Extra or missing chromosomes can lead to chromosomal
conditions that cause miscarriage or result in the birth of a child with mental or physical disabilities.

Fragments of DNA float in our blood. During pregnancy, some of the  DNA fragments in the mother’s blood comes from the baby’s placenta. By sampling the mother’s blood, Generation tests the DNA from the placenta to determine the chance that the baby has a chromosomal condition.

 

What do the Generation NIPT options detect?

Generation

  • Common conditions of Down syndrome, Edward’s syndrome and Patau syndrome, which are due to additional chromosomes 21, 18 and 13 respectively
  • Sex chromosome conditions which are due to a gain or a loss of one of the sex chromosomes of X and Y
  • Fetal sex (optional)

Generation 46

  • Common and rare conditions due to a gain or loss of any of any of our 23 pairs of chromosomes, including our sex chromosomes
  • Rare conditions due to gain (duplication) or loss (deletion) of part of the chromosome
  • Includes all conditions detected in Generation NIPT
  • Fetal sex (optional)

Generation Plus

  • Common conditions of Down syndrome, Edward’s syndrome and Patau syndrome, which are due to additional chromosomes 21, 13 and 18 respectively
  • Sex chromosome conditions which are due to a gain or a loss of one of the sex chromosomes of X and Y
  • Five very rare conditions due to a tiny loss (microdeletion) of part of a chromosome
  • Fetal sex (optional)

How it works

There are only four simple steps to having your Generation test.

2. Prepare for your collection

Prepayment is required for Generation online here. Record your receipt number on the request form and sign the Patient Consent section before blood collection. There is no Medicare rebate for this test.

 

 

4. See your doctor to get your results

Your result is provided to your doctor, who will discuss this with you. Genetic counselling is offered free of charge for all high risk results.

1. Talk to your doctor about Generation NIPT

Discuss with your doctor the most appropriate Generation option for you, and they will complete a request form. Download the form to take to your doctor here.

 

 

NIPT testing can provide important health information on your baby. See your doctor, who can discuss the appropriate Generation option with you, and request the test.

2. Prepare for your collection

Prepayment is required for Generation. Pay online or over the phone on 1800 822 999. Record your receipt number on the request form. You will also need to sign the Patient Consent section on the request form before blood collection.

3. Get your sample collected

You can have your sample collected at any of our collection centres. No booking is required. Generation Plus is only collected Mondays.

4. See your doctor to get your results

Your result is provided to your doctor, who will discuss this with you and action any relevant findings. Genetic counselling is offered free of charge for all high risk results.

Frequently Asked Questions

Generation NIPT can be used to obtain important and accurate information about the health of your developing baby in the first trimester (from 10 weeks), with little or no risk to the pregnancy.

This screening test may be an option for you if:

  • You wish to know detailed health information about your baby
  • You will be 35 years or older at the time of delivery (32 years or older for a twin pregnancy)
  • You have an abnormal or “positive” first trimester serum screen
  • Your ultrasound has revealed concerns or abnormalities with fetal growth and / or development
  • You have a personal or family history suggestive of a chromosome disorder (eg. Down syndrome)

What’s more, clinical best practice guidelines from Australian and international medical societies recommend that all pregnant women, regardless of risk status, be given the opportunity to have NIPT and other available prenatal screening and diagnostic tests.

NIPT is a highly accurate screen for chromosomal conditions and is much better than older style screening tests at identifying whether a baby is or isn’t affected by the conditions being tested.

However, sometimes a pregnancy can be identified as high risk by NIPT but the baby does not have a chromosomal condition. The chance of this happening often depends on the age of
the mother and the specific condition.

The fact that this can happen is the reason that all high risk results should be confirmed by a diagnostic test (amniocentesis or chorionic villus sampling) to clarify if the baby does or does not have a chromosomal abnormality.

All of this can be explained by the genetic counsellor during genetic counselling that is available for all high risk NIPT results from Genomic Diagnostics.

The Generation test only addresses chromosomal changes. It doesn’t test for other genetic and non-genetic problems that may be present in a baby. No test can guarantee a baby will not have any medical issues.

 Generation NIPTFirst Trimester Screening
Chromosomal conditions detectedAll conditions across all chromosomes (depending on option chosen)Common conditions only of Down, Edwards and Patau syndromes
Fetal sex detectedYesNo
Available from10 weeks onwards11-13 weeks ony
Sensitivity99%85%
Specificity99%95%
ResultHigh or low riskRisk ratio in conjunction with Nuchal translucency ultrasound
Positive predictive value (ratio of patients who truly have a positive result on diagnostic testing)45%7-10%

Reference: The Royal Australian and New Zealand College of Obstetricians and Gynaecologists 2018 guidelines: Prenatal screening and diagnostics testing for fetal chromosomal and genetic conditions.

Your NIPT report will include one of two possible results for chromosomes 21, 18, 13, and the sex chromosomes (X and Y).

If you have a Generation 46 or Generation Plus NIPT, it will also include information on other chromosomes and microdeletions.

Low risk result – this means that it is very unlikely that your pregnancy is affected by the chromosomal conditions screened by the test.

High risk result – this means that there is an increased chance that your baby has too many or too few copies of one or more chromosomes or parts of chromosomes.

However, as Generation is a screening test, a diagnostic test such as amniocentesis or chorionic villus sampling (CVS) is required to confirm a high risk result.

If your result shows a high risk for having a baby with a chromosomal condition, we will arrange for a genetic counsellor to contact you within 48 hours of request by your doctor. They will discuss with you what the result means, the options available and answer any questions you may have. This is a free service. You should also discuss the result with your doctor.

Fetal Sex: An additional benefit to Generation is that you may choose to have the sex of your baby revealed.
This is automatically reported unless you opt out on the request form.

Genomic Diagnostics has a partnership with Illumina, Inc to undertake Generation Plus testing. Your samples and request form will be sent to the Illumina laboratory in California, USA for testing.

Please note: As this website contains only general educational information, professional advice from your medical practitioner should be sought before applying this information to particular circumstances. You should not rely on any information contained in this website without first obtaining professional advice. Prices are correct at time of publishing and are subject to change without notice.

Your Reproductive Health Test Journey

Starting a family is an exciting and sometimes confusing time. There are a number of genetic tests you may like to consider during this. Please discuss them with your doctor.

  • Some pregnancies may need further genetic testing based on family history, ultrasound findings or high risk NIPT results.  Talk to your doctor for further information.

Generation Tests

$425

Screening for the most common chromosomal changes.

  • Trisomy 21 (Down syndrome), Trisomy 18 (Edwards syndrome) & Trisomy 13 (Patau syndrome)
  • Specific sex chromosome changes
  • Fetal sex

Results available within 3 – 5 days of sample arrival at laboratory.

$449

Screening all chromosomes for changes.

  • Chromosomal and subchromosomal changes  >7Mb
  • Specific sex chromosome changes
  • Fetal sex

Results available within 3 – 5 days of sample arrival at laboratory.

$799

Screening for the most common chromosomal changes plus specific microdeletion syndromes.

  • Trisomy 21 (Down syndrome), Trisomy 18 (Edwards syndrome) & Trisomy 13 (Patau syndrome)
  • Specific sex chromosome changes
  • Fetal sex
  • Five microdeletion syndromes including 22q11 deletion (DiGeorge syndrome)

Results available within 9- 13 days of sample arrival at laboratory.

Leading the way to improved health

Our dedicated team are committed to ensuring the best quality
results in the shortest turnaround time.