Colorectal cancer is one of the most common cancers in Australia. While most cases develop sporadically, some are linked to inherited genetic conditions that increase cancer risk. These inherited colorectal cancer syndromes occur when specific genetic changes are passed down through families.
Genetic testing can help identify whether an inherited condition is present. This information may guide cancer screening, prevention strategies and medical management, and can also be important for family members who may share the same risk.
Colorectal cancer is one of the most common cancers in Australia. While most cases develop sporadically, some are linked to inherited genetic conditions that increase cancer risk. These inherited colorectal cancer syndromes occur when specific genetic changes are passed down through families.
Genetic testing can help identify whether an inherited condition is present. This information may guide cancer screening, prevention strategies and medical management, and can also be important for family members who may share the same risk.
Lynch syndrome is one of the most common inherited colorectal cancer syndromes. It increases the risk of colorectal cancer, endometrial cancer and some other cancers.
Identifying Lynch syndrome can support tailored cancer screening and early detection strategies for patients and their relatives.
Some inherited conditions lead to the development of multiple colorectal polyps, which can significantly increase cancer risk.
Polyposis panels assess genes associated with both adenomatous and non‑adenomatous polyposis syndromes. These tests may be helpful for individuals with multiple polyps, early‑onset disease, or features suggestive of a hereditary polyposis condition.
This broader panel assesses genes linked to hereditary colorectal and endometrial cancer syndromes, including polyposis and related gastrointestinal cancers.
It may be considered when there is a personal or family history involving both colorectal and endometrial cancer, or when the pattern of cancer does not clearly match a single inherited syndrome.
Genetic testing can help clarify whether an inherited condition is contributing to cancer risk. This may allow for:
Not everyone tested will receive a genetic diagnosis, and a normal result can also provide reassurance.
