



Some people and families have a history of cancer that cannot be explained by a single cancer type or syndrome. In these situations, a comprehensive hereditary cancer panel may be recommended. These tests look at a wide range of genes associated with inherited cancer risk across multiple organ systems.
Comprehensive panels can help clarify whether an inherited condition is contributing to cancer risk, particularly when there are multiple cancers in a family, cancers diagnosed at younger ages, or an unclear pattern of inheritance. Results may support personalised screening, risk management, and treatment decisions, and can provide important information for family members.
Testing multiple genes at once can reduce the need for repeat testing and may identify genetic causes that would otherwise be missed.
A comprehensive panel may be considered if there is a complex family history of cancer, multiple cancer types across generations, young‑onset cancers, or when previous testing has not identified a genetic cause.
Not necessarily. The most appropriate test depends on clinical history. In some cases, a targeted panel is preferred. A healthcare professional or genetic counsellor can help determine whether comprehensive testing is suitable.
Testing usually requires a blood sample, which is analysed in the laboratory for inherited gene changes associated with cancer risk.
If an inherited gene change is identified, family members may choose to seek genetic advice and testing. This can help clarify their own risk and guide screening or prevention options.