Test description
Testing of an expanded set of genes associated with the common and rare hereditary cancer syndromes in patients with complex or overlapping personal or family cancer histories.
Test information
BRAoVO™ Pan Cancer gene panel
1. Testing of a patient with cancer where there is also a family history of one or more cancer types of breast, ovarian, colorectal, polyposis, pancreatic, endometrial, prostate, melanoma, renal, endocrine, sarcoma, CNS, Schwannoma and Gorlin syndromes.
2. Testing of an unaffected patient where there is a complex family history of two or more cancer types of breast, ovarian, colorectal, polyposis, pancreatic, endometrial, prostate, melanoma, renal, endocrine, sarcoma, CNS, Schwannoma and Gorlin syndromes.
AIP, APC, ATM, AXIN2, BAP1, BARD1, BMPR1A, BRCA1, BRCA2, BRIP1, CDC73, CDH1, CDK4, CDKN1B, CDKN2A,CHEK2, CTNNA1, DICER1, EPCAM, FH, FLCN, GREM1, HOXB13, KIT, LZTR1, MAX, MEN1, MET, MITF, MLH1, MLH3, MSH2, MSH3, MSH6, MUTYH, NBN, NF1, NF2, NTHL1, PALB2, PDGFRA, PMS2, PMS2CL, POLD1, POLE, POT1, PRKAR1A, PTCH1, PTEN, RAD51C, RAD51D, RB1, RET, RNF43, SCG5, SDHA, SDHAF2, SDHB, SDHC, SDHD, SEC23B, SMAD4, SMARCA4, SMARCB1, SMARCE1, STK11, SUFU, TERT, TMEM127, TP53, TSC1, TSC2, VHL, WRN, WT1
Massively Parallel Sequencing
6 weeks
$950 if not Medicare eligible
Cancer Genetics Request form preferred. Standard pathology request form accepted.
Blood x 2
EDTA
2 x Bloods taken at 10 minute intervals. Pre-test genetic counselling required. Patient to sign a consent form prior to testing, which stays with the specialist.