Test description
Guidelines recommend testing to confirm the diagnosis of an inherited CRC syndrome in a patient with a personal history of disease in the following circumstances:
- APC gene testing is indicated in patients with ≥10 colorectal adenomas before age 30, or ≥20 colorectal adenomas regardless of age.
- MUTYH gene testing is indicated for patients with ≥20 colorectal adenomas at any age, but could also be considered in patients with fewer polyps following review by a familial cancer service, and patients with an FAP phenotype but no identifiable APC variant.
Test information
Test name
FAP Gene Panel
Clinical indication
Used for investigation of FAP/MAP in patients with adenomatous polyposis where there is a familial risk of ≥10%.
Gene(s)
APC, MUTYH
Method
Massively Parallel Sequencing
Turn around time
4 weeks
Medicare eligibility
73355 – conditions apply
Price
$479 if not Medicare eligible
Test request form
Cancer Genetics Request form preferred. Standard pathology request form accepted.
Sample type
Blood x 2
Collection type
6mL EDTA
Special instructions
2 x Bloods taken at 10 minute intervals. Pre test genetic counselling required. Patient to sign consent form prior to testing.