Test description
Detectionof specific pathogenic variants in the PDGFRA or KIT genes provide access to the use of tyrosine kinase inhibitor therapy in the adjuvant or metastatic setting. A BRAF pathogenic variant may be associated with resistance to these therapies.
Test information
Test name
GIST solid tumour panel
Clinical indication
Testing of gastrointestinal stromal tumour tissue to determine specific TKI therapy.
Gene(s)
DNA: KIT, PDGFRA, BRAF, KRAS, NRAS, PIK3CA
RNA: NTRK fusion, FGFR fusion
Method
NGS Oncomine Precision Assay
Turn around time
5 business days from receipt of sample
Medicare eligibility
N/A
Price
DNA only: $425
DNA & RNA: $799
Test request form
Somatic Genetic Testing Request Form
Sample type
FFPE Tumour Tissue
Collection type
Special instructions
6 x 5µm slides plus 1 x H&E-stained slide required