Your genetic make up (your DNA) provides a crucial role in how your body responds to medication.
Pharmacogenomic (PGx) DNA testing empowers you and your healthcare provider to develop a tailored treatment plan for maximum effectiveness.
Taken medications in the past and found them not to work?
Pharmacogenomic Testing (PGx) of your DNA may be able to help
Depending on your unique genetic makeup, you may process a medication:
This is because we all process medications differently.
If we are all given the same medication at the same dose, we react in four different ways:
By testing our DNA, we can work out how we may react to each medication.
Thus testing can help your doctor determine the right medication at the right dose for you.
Pharmacogenomic testing is a powerful tool that empowers both you and your doctor to make informed, personalized decisions about your medication, helping you achieve better health outcomes quickly and safely.
Talk to your doctor about your options, and request an PGx test.
Visit one of our centres to get your sample collected or order an online kit for delivery direct to your home.
Your doctor will discuss any relevant findings.
Pharmacogenomics is the study of the role that DNA variants play in drug efficacy. The DNA variants may either be inherited, and part of an individual’s inherited genetic make-up, or may be acquired in a person’s tumour (non-heritable) and can be used to predict drug responses or the likelihood of adverse drug reactions.
In addition to specific tests available for the enzymes thiopurine S-methyltransferase (TPMT) and glucuronyltransferase (UGT1A1), the Pharmacogenomic (PGx) Multi panel covers enzymes involved in breaking down medications used in the mental health area and the pain area as well as a wide range of other medications.
In the case of cancer treatment, the mutations acquired in a person’s tumour (non-heritable) may make the tumour more sensitive or resistant to treatment targeted gene, or gene pathway, specific treatment.
Providing the patient with the right dose of the right medicine is the aim of personalised medicine. Variation in an individual’s genetic makeup compared to others in the general population can affect their response to medications because some of these variations affect drug metabolic pathways. In some cases, this may result in sub-optimal therapeutic levels, or conversely, toxic adverse effects.
Discuss and request a Pharmacogenomics test with your patient.
Your patient can chose to visit a centre for a blood collection or have a swab kit sent to their home.
Discuss your patient's results with them and the next steps.
