Test description
Deletion of the DAZ cluster of genes on the Y chromosome are a common cause of spermatogenesis failure (azoospermia). The size and gene content of the deletions is associated with the clinical outcome for the patient. Determining the presence and genomic location of these deletions assists in determining the appropriate modes of reproductive assistance for patients.
Test information
Test name
Y chromosome microdeletion (DAZ deletion)
Clinical indication
In the investigation of male infertility, to determine genetic cause for azoospermia or oligozoospermia
Gene(s)
AZFa, AZFb, AZFc SRY
Method
Conventional PCR and capillary electrophoresis
Turn around time
14 days
Medicare eligibility
No
Price
$150
Test request form
Standard business unit request form
Sample type
Blood
Collection type
6mL EDTA tube
Special instructions
None