Lymphocyte gene rearrangements test

Determines clonality in lymphoproliferative disorders by analyzing gene sequences.

Test description

B-cell immunoglobulin heavy chain (IgH) gene rearrangements

This test is for the IgH gene rearrangements (FR1, FR2 and FR3) and will detect greater than 80% of B-cell lymphoproliferative disorders.

T-cell Receptor (beta and gamma) gene rearrangements:

This test is for detecting monoclonality of T lymphocytes using primers targeted at both beta and gamma gene rearrangements, and will detect at least 90% of T-cell lymphoproliferative disorders.

Test information

Test name

T &/or B cell rearrangement

Clinical indication

To determine clonality in lymphoproliferative disorders

Gene(s)

IGH

Method

Conventional PCR and fragment analysis

Turn around time

2 weeks

Medicare eligibility

No

Price

B Cell gene rearrangement: $130

T Cell gene rearrangement: $180

Test request form

Standard business unit request form

Sample type

Blood or bone marrow or Lymph node or Tumour

Collection type
Special instructions

None

FAQ

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Resources

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